representative publications
Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jäger E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A*, Stehlik C*. NLRP3 licenses NLRP11 for inflammasome activation in human macrophages. Nature Immunology, 2022, 23, 892-03. PMID:35642062 | pdf
press coverage: Cedars Sinai | pdf | News Wise | pdf | Science News Net | pdf | News Medical Life Sciences | pdf | Daytonews | pdf
Khare, S, Dorfleutner, A, Bryan, NB, L., Yun, C, Radian, AD, de Almeida, L, Rojanasakul, Y, Stehlik, C. An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in macrophages. Immunity, 2012, 36, 464-476. PMID:22361007 | pdf
Featured as a Research Highlight in Nature Reviews Immunology.Nature Reviews Immunology, 12, 358 | pdf | Featured as a Research Highlight in Nature Immunology. Nature Immunology, 13, 358 | pdf | press coverage: Northwestern University | pdf | The DailyNorthwestern | pdf | EurekAlert | pdf | LabSpaces | pdf | MediLexicon | pdf | Medical News Today | pdf | recommended by F1000Prime | pdf 
de Almeida, L, Khare, S, Misharin, AV, Patel, R, Wallin, M, Perlman, HR, Greaves, DR, Hoffman, HM, Dorfleutner, A*, Stehlik, C*. The PYRIN domain-only protein POP1 inhibits inflammasome assembly and ameliorates inflammatory disease. Immunity, 2015, 43, 264-276. PMID:26275995 | pdf
Selected for display at the Immunity website | pdf | highlighted with a Commentary by Shimada K. Timothy R. Crother T.R., and Arditi, M. (2015) POPsicle for Fever! Cooling Down the Inflammasome. Immunity, 43, 213-215 | pdf | press coverage: Northwestern University | pdf | the Rheumatologist | pdf
Ratsimandresy, R, Chu, HL, Indramohan, M, Gangopadhyay, A, Dorfleutner, A*, and Stehlik, C*. The PYRIN domain-only protein POP2 regulates inflammasome priming and activation. Nature Communications, 2017, 8, p15556. PMID:28580931 | pdf
Khare, S, Ratsimandresy, RA, de Almeida, L, Cuda, CM, Rellick, SL, Misharin, AV, Wallin, MC, Gangopadhyay, A, Forte, E, Gottwein, E, Perlman, H, Reed, JC, Greaves, DR, Dorfleutner, A*, Stehlik, C*. The PYRIN domain-only protein POP3 inhibits AIM2-like receptor inflammasomes and regulates responses to DNA virus infections. Nature Immunology, 2014, 15, 343-345, PMID:24531343 | pdf
highlighted with a News and Views Commentary by Krishnaswamy J.K., Liu D. and Eisenbarth S.C. (2014) POP goes the inflammasome. Nature Immunology, 15, 311-313 | pdf | selected as the cover article | pdf | featured by the Austrian Presse Agentur (APA) and MedOnline | pdf | jimdo.com (in Italian) | pdf | Nature Asia | pdf | Feinberg News | pdf
Chu, HL, Indramohan, M, Ratsaimandresy, RA, Gangopadhyay, A, Morris, EP, Monack, DM, Dorfleutner, A*, and Stehlik, C*. The oxidized phospholipid oxPAPC protects from septic shock by targeting non-canonical inflammasome in macrophages, Nature Communications, 2018, 9, 996, PMID:29520027 | pdf
Stehlik C, Dorfleutner A. COPs and POPs: modulators of inflammasome activity. J Immunol. 2007, 179, 7993-7998. PMID:18056338 | pdf
Dorfleutner A, Chu L, Stehlik C. Inhibiting the inflammasome: one domain at a time. Immunol Rev. 2015, 265, 205-216. PMID:25879295 | pdf