stehlik-dorfleutner lab publications 2021-2025
Carriere J, Dorfleutner A*, Stehlik C*. NLRP7: From inflammasome regulation to human disease. Immunology 2021, 163, p363-376. PMID:34021586 | pdf
Dagvadorj J, Mikulska-Ruminska K, Tumurkhuu G, Ratsimandresy RA, Carriere J, Andres AM, Marek-Iannucci S, Song Y, Chen S, Lane M, Dorfleutner A, Gottlieb RA, Stehlik C, Cassel S, Sutterwala FS, Bahar I, Crother TR, Arditi M. Recruitment of pro-IL-1α to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation. Proceedings of the National Academy of Science USA 2021, 118, e2015632118. PMID:33361152 | pdf
Gangopadhyay A, Devi S, Tenguria S, Carriere J, Nguyen H, Jäger E, Khatri H, Chu LH, Ratsimandresy RA, Dorfleutner A*, Stehlik C*. NLRP3 licenses NLRP11 for inflammasome activation in human macrophages. Nature Immunology 2022, 23, p892-903. PMID:35642062 | pdf | press coverage: Cedars Sinai | pdf |
de Almeida L, Devi S, Indramohan M, Huang QQ, Ratsimandresy RA, Pope RM, Dorfleutner A*, Stehlik C*. POP1 inhibits MSU-induced inflammasome activation and ameliorates gout. Frontiers in Immunology 2022, 13, 912069. PMID:36225929 | pdf
Dorfleutner A*, Stehlik C*. Cellular signaling, molecular activation, and regulation of the noncanonical inflammasome. chapter 9 in Inflammasome Biology: Fundamentals, Role in Disease States, and Therapeutic Opportunities. ed Pablo Pelegrin. Academic Press 2022. ISBN: 9780323972062 | pdf
Devi S, Indramohan M, Jäger E, Carriere J, Chu LH, de Almeida L, Greaves DR, Stehlik C*, Dorfleutner A*. CARD-only proteins regulate in vivo inflammasome responses and ameliorate gout. Cell Reports 2023, 42, 112265. PMID:36930645 | pdf
Devi S, Stehlik C*, Dorfleutner A*. Protocol to create a murine subcutaneous air pouch for the study of monosodium urate crystal-induced gout. STAR Protocols 2024, 5, 102888. PMID: 38358882 | pdf
Dorfleutner A, Stehlik C, Jefferies C. Mx1-ing it up-Mitochondrial relay for interferon-dependent, unconventional IL-1β release in SLE monocytes. Immunity 2024, 57, p2483-2486 . PMID: 39536711 | pdf
Chang C-Y, Hernández-Armengol R, Paul K, Lee JY, Nance K, Shibata T, Sue P, Stehlik C, Gibb DR. The Nrf2 Activator CDDO-Imidazole Suppresses Inflammation-Induced red Blood Cell Alloimmunization. Antioxidants 2025, 14, p678. PMID: 40563311 | pdf
Tumurkhuu G, Perri G, Moore R, Huo L, Kumar AN, Ainsworth R, Oliver T, Santos GDL, Gibb D, Carriere J, Yu JM, Abuav R, Forbess L, Wallace DJ, Ishimori M, Shon W, Stehlik C, Jefferies CA. Loss of Tripartite Motif–Containing Protein 21 and UVB-Induced Systemic Inflammation by Regulating DNA-Sensing Pathways. Arthritis & Rheumatology 2026, 78, p172-183. PMID: 40524344 | pdf